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An interview with George Daley

Posted by on September 22nd, 2017

This interview by Aidan Maartens appeared in Development, Vol 144 Issue 18 George Daley is Dean of the Faculty of Medicine, Professor of Biological Chemistry and Molecular Pharmacology, and Caroline Shields Walker Professor of Medicine at Harvard Medical School. A former Howard Hughes Medical Institute Investigator and President of the International Society for Stem Cell[…]

In Development this Week (Vol. 144, Issue 17)

Posted by on August 29th, 2017

Here are the highlights from the current issue of Development:   AdamTS-A keeps the CNS in shape The Drosophila central nervous system (CNS) is covered by a thick basement membrane that mediates interactions with glial cells and governs the shape of the tissue. Basement membranes are formed from a meshwork of secreted extracellular matrix (ECM) proteins and must be[…]

In Development this Week (Vol. 144, Issue 16)

Posted by on August 15th, 2017

Here are the highlights from the current issue of Development:   PLCζ ‘waves in’ mammalian oocyte activation At fertilisation, fusion of the sperm with the oocyte activates a slew of downstream processes to kick-start embryogenesis. This ‘oocyte activation’ event induces the cortical reaction to prevent polyspermy, triggers oocyte metabolic and DNA synthesis pathways, and reactivates meiosis. In[…]

In Development this Week (Vol. 144, Issue 15)

Posted by on August 1st, 2017

Here are the highlights from the current issue of Development:   X-citing insights into dosage compensation The non-coding RNA Xist plays a key role in the process of X chromosome inactivation (XCI) and is thus essential for dosage compensation of X-linked genes in females. The 5′ region of Xist RNA contains a conserved element termed the A-repeat that is required for[…]

The Drosophila fly brings to light the role of morphogens in limb growth

Posted by on July 5th, 2017

• Scientists at IRB Barcelona clarify the function of the genes that drive wing development in the fruit fly Drosophila melanogaster. • Published in the journal eLife, this study unveils that the Dpp morphogen is necessary for wing growth but that its gradient does not govern this process. • Understanding the development of limbs in[…]

Going format-free

Posted by on May 30th, 2017

This Editorial originally appeared in Development, Volume 144, Issue 11   Katherine Brown, Olivier Pourquié   As some readers will already be aware, we have recently introduced a new ‘format-free’ submission policy. We’ve been delighted by the early feedback on this – from what we’re hearing, this has been a popular move and will help make[…]

Our latest research on Hormonal regulation of temporal gene expression in neural stem cells

Posted by on May 16th, 2017

http://around.uoregon.edu/content/study-brain-formation-finds-possible-link-human-disease @ http://www.doelab.org/ elife https://elifesciences.org/content/6/e26287   (No Ratings Yet) Loading…

Development introduces format-free submission

Posted by on April 20th, 2017

At Development, we are committed to making submission as easy as possible for our authors. We realise that submitting a paper to any journal can be a lengthy process: authors are asked to comply with detailed journal-specific guidelines without knowing whether the paper will be accepted or even peer-reviewed. We are therefore delighted to announce[…]

A New Way To Look At Human Development

Posted by on March 29th, 2017

  Throughout history, the desire of scientists to understand physiology and disease by thoroughly studying anatomical features, has always faced an intractable limitation: they cannot simply see through the tissue! Dissection has therefore been the modus operandi of anatomists: from Galen’s pioneering studies, to modern day biologists who routinely section tissues to label structures for[…]

Meet Our Scientists VIDEO: Marco Milán: “To study how cells communicate with each other, perhaps the best model organism is the fruit fly”

Posted by on February 15th, 2017

The “Meet Our Scientists” video entitled “Our relative the fly” presents the research performed by Marco Millán on the cellular and molecular mechanisms underlying the regulation of tissue growth during normal development, tissue homeostasis, and tumorigenesis.     Marco Milán, ICREA research professor, leads the Development and Growth Control Laboratory at IRB Barcelona. In the[…]